The Importance of Cysteine vs. Cystine
ImmunoPro and RenewPro whey proteins contain exceptional levels of naturally occurring Cysteine. It is the optimal component for the intracellular production of Glutathione (GSH). Cysteine is very scarce in our modern diet and therefore Glutathione production is limited and deficiency is prevalent. If Cysteine undergoes any heating or processing, as all conventional dairy and dairy by-products do, it is denatured and converted to Cystine. Cystine is the form that is found in all of the high-end whey proteins, as they are all by-products. ImmunoPro and RenewPro are unique as they are the only non-denatured native whey products and contain naturally occurring Cysteine.
An important note on the synthesized free form amino acid L-cysteine, it can have adverse effects in supplemental doses with sensitive individuals or those who have any heavy metal accumulation.
Regarding Whey Protein Concentrate: The journal Immunology reports: The bioactivity occurs through the ability of the protein concentrate to help replenish Glutathione levels via continuous dietary provision of Glutathione precursors, especially Cysteine, during lymphocyte proliferation, thus supporting an optimal immune response. This process seems to not only increase intercellular levels of Glutathione and precursors at the time of ingestion, but also builds up stores of these substances within the cells which lasts for a substantial post-ingestion time interval.” Fidelus RK, Tsan MF. GSH and lymphocyte activation: a function of aging and autoimmune disease. Immunology 61: 503-508, 1987
* Native: of or relating to the naturally occurring conformation of a macromolecule, such as a protein. Constituting the original substance or source b : found in nature especially in an unadulterated form <conversion of a native protein to a denatured protein>
* Native Protein: The concept of a protein in its natural state, in the cell, unaltered by heat, chemicals, enzyme action, or the exigencies(distress) of extraction.
** (Denature: To cause the tertiary structure of (a protein) to unfold, as with heat, alkali, or acid, so that some of its original properties, especially its biological activity, are diminished or eliminated.) It is not possible for a protein to be undenatured.
*** Analysis of protein as determined by an independent laboratory using the SDS PAGE Gel method. This is the industry accepted method to determine the actual biological activity of a milk protein.